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The following article features coverage from the American Society of Nephrologyrsquo Kidney Week 2021. Click here to read more of Renal Urology Newsrsquo conference coverage. Chlorthalidone, a drug approved by the FDA in 1960, significantly improves systolic blood pressure SBP control at 12 weeks compared with placebo in patients with advanced chronic kidney disease CKD and poorly controlled hypertension, according to data presented at the American Society of Nephrologyrsquo Kid
stanley cups ney Week 2021 and published concomitantly in the Ne
stanley tumbler w England Journal of Medicine.This study establishes the efficacy of low dose chlorthalidone as an effective drug to treat hypertension in patients with stage 4 CKD, lead investigator Rajiv Agarwal, MD, MS, professor of medicine at the Indiana University School of Medicine in Indianapolis, told Renal Urology News.The double-bl
stanley becher ind Chlorthalidone in Chronic Kidney Disease CLICK Trial included 160 patients with stage 4 CKD randomly assigned to receive chlorthalidone at an initial dose of 12.5 mg per day, with increases every 4 weeks if needed to a maximum of 50 mg per day, or placebo. At randomization, the mean 24-hour ambulatory SBP was 142.6 mm Hg in the chlorthalidone group and 140.1 mm Hg in the placebo group.From baseline to 12 weeks, mean SBP declined by 11.0 mm Hg in the chlorthalidone group and 0.5 mm Hg in the placebo group, a significant 10.5 mm Hg lower SBP in the chlorthalidone gr Prou Baseball Roundup: Red Sox Salvage Finale
There was no hug 鈥?only the odd handoff
stanley tumblers of a silver trophy and obligatory niceties.Finally, the delicious moment everyone has been waiting for had arrived, that shining moment when NFL commissioner Roger Goodell would stride to the podium and present the Super Bowl MVP 鈥?the same man Goodell had punished for Deflategate 鈥?with the Pete Rozelle Trophy.This was a bona fide get-yer- popcorn event after Tom Brady was suspended four games by Goodell for his still-debated role in Deflategate. Goodell may have been overwhelmed by boos after the Patriots historic victory, but the two men were polite toward one another on Monday, even if they
stanley quencher werent completely buddy-buddy. Goodell pointed out that Brady and coach Bill Belichick have raised the bar for performances and added that it was a great honor for us, for me personally to hand over the MVP trophy.For his part, Brady said: Its an honor to have the commissioner present us with this trophy. And with that, Deflategate officially seems to be over.There was to be no repeat of February 2015, when, with Deflategate only weeks old, the two men hugged it out as Brady accep
stanley italy ted his fourth MVP trophy. The lone mention of the incident after the Super Bowl LI win came from Patriots team owner Robert Kraft, who brought up the issue when accepting the Super Bowl trophy Sunday night.Join your neighbors and subscribe!Award-winning coverage on breaking news and todays top stories in and around the Upper Valley. Whether it s arts, sports, opini
