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hdfv Sharapova hits back at Wozniacki in scheduling row
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  Alnylam Pharmaceuticals has announced that it will advance a systemically delivered RNAi therapeutic for the treatment of hypercholesterolemia as its next clinical development program. This program, in collaboration with聽University of Texas Southwestern Center聽at Dallas, is focused on evaluating new approaches for reducing LDL cholesterol levels using RNAi therapeutics directed to the disease target called proprotein convertase subtilisn/kexin type 9, or PCSK9. Alnylam expects to submit an investigational new drug (IND) application for this program in 2007.PCSK9 is a gene involved in the metabolism of LDL cholestero new balance nb 530 l, or so-called "bad cholesterol." The normal role of  yeezy 500 the PCSK9 protein is to break down the cell surface receptor for LDL; when there is less PCSK9 protein, there is more receptor on the cell surface to remove LDL from the bloodstream. In human stud yeezy ies, researchers at UT Southwestern Medical Center have discovered that mutant forms of PCSK9 that have increased activity are   Samia Shahid, the British-Pakistani adidas samba vegan  woman raped and murdered in a su adidas samba bianche spected "honour killing" in Pakistan, texted聽a friend asking her to pray she 鈥渃ame back alive鈥?hours before boarding a flight, it has emerged.Samia Shahid, o newbalance 9060 riginally from Bradford, died while visiting her relatives in her ancestral village of Dhok Khinger in Pakistan. Her family had initially claimed she had a heart attack, but an autopsy revealed she had been raped and then strangled.British woman raped before being killed for 'honour' in PakistanA 43-page police report, seen by the Mail Online, by an official connected with the case, said that the day before she was due to fly to Islamabad for the week-long stay, she had texted her friend saying,聽鈥淧ray I come bk alive on 21jul my psyco cuzzan u see鈥?鈥?referring to her former husband Muhammad Shakeel.The report had also concluded that her father had held her down while Shakeel raped her. Police has charged Shahid鈥檚 ex-husband and father with her murder. 鈥淲e have comp