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New findings suggest that late-onset Alzheimer鈥檚 Disease is driven by epigenetic changes 鈥?how and when certain genes are turned on and off 鈥?in the brain. Results are published inNature Genetics.Research led byRaffaella Nativio, PhD, a former research associate of Epigenetics,Shelley Berger, PhD, a professor of Genetics, Biology and Cell and Developmental Biology and Director of the Epigenetics Institute, andNancy Bonini, PhD, a professor of Biology and Cell and Developmental Biology, all in the Perelman School of Medicine at the University of Pennsylvania, used post-mor
dunk chaussure tem brain tissue to compare healthy younger and older brain cells to those with Alzheimer鈥檚 Disease. The team found evidence that epigenetic regulators disable protective pathways and enable pro-disease pathways in those with the disease.鈥淭he last five years have seen great efforts to develop therapeutics to treat Alzheime
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stanley cup s thought they were in a film as evergreen Roma veteran Francesco Totti came off the bench to secure a potentially crucial 3-2 win over Torino on Wednesday.Roma were trailing 2-1 with four minutes to
adidas samba rose play after Josef Martinez had added to Andrea Belotti's first-half penalty in the 80th minute for the visitors.But one-club man Totti, who has seen his chances of a contract extension hit by a series of spats with coach Luciano Spalletti this se
ugg hausschuhe ason, stunned the stadium by turning the game on its head.Confidence key for Keita as Roma await Zidane's Real"The roar in the stadium for Totti was impressive," said Spalletti, a coach who was in charge of Roma when the Stadio Olimpico was virtually full at every home game during his previous four-year spell in 2005-2009.Just 23 seconds after replacing Malian midfielder Seydou Keita, Totti slid in at the back post to meet a downward header from Miralem Pjanic's free kick to guide the ball pas
