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  Onconova Therapeutics, Inc. announced t dunk nike hat tolerability and favorable anti-tumor activity data from a Phase 1 trial evaluating oral rigosertib, a dual pathway inhibitor, in patients with advanced solid tumors including refractory metastatic head and neck cancer were presented at the American Association for Cancer Research (AACR) Annual Meeting. The presentation was made by Antonio Jimeno, MD, PhD, of the University of Colorado School of Medicine and Director of the University鈥檚 Head and Neck Cancer Medical Oncology Program.The oral presentation by Dr. Jimeno entitled, 鈥淧hase 1 and molecular correlates study of oral rigosertib in patients with refractory metastatic head and neck cancer and advanced solid tumors,鈥?reported on the safety and activity of rigosertib in 48 patients. The objectives of this study w air forces ere to define dose limiting toxicity, to characterize the pharmacokinetic (PK) profile, and to identify anti-tumor activity. Oral rigose nike dunk low rtib was generally well tolerated. Notably, t  ISLAMABAD:Consumers of petrol and diesel are likely to get relief as the government is likely to cut petroleum products prices in May after it kept increasing their prices during the last several months following fluctuations in global oil prices.However, the government is expected to increase the prices of light diesel and kerosene.The Oil and Gas Regulatory Authority (Ogra) has sent its recommendations regarding petroleum prices to the Ministry of Petroleum on Friday.According to Ogra鈥檚 calculation, the prices of petrol and high speed diesel are likely to be reduced by Rs1 per litre. However, the price of light diesel is expected to increase by Rs10 per litre and adidas samba og  kerosene by Rs15 per litre.Petrol, diesel prices increased by Rs1 pe uggs hausschuhe r litreThe new prices will be implemented after getting the nod of Prime Minister Nawaz Sharif with effect from May 1, 2017.The petroleum consumers have been facing partia stanley l increase in oil prices during the past several months due to fluctuations in global o