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Wdav Juvaris BioTherapeutics Announces Positive Data from Clinical Trial of JVRS-100 Adjuvanted Flu Vaccine
  Karus Therapeutics ( nike air force1 鈥楰arus鈥? has announced that the first patients have been dosed in a Phase I study for its lead candidate, KA2237. This is the Company鈥檚 first product to enter clinical trials. KA2237 is a dual-selective inhibitor of two PI3K isoforms, p110尾 and p110未. Inhibiting these two isoforms combines a asics schuhe n immunotherapeutic response and a direct effect on tumor growth, through selective, targeting of the PI3K pathway. Karus believes that KA2237 has broad therapeutic applicability in the treatment of hematological and solid tumors, as a single agent and in combination with other drugs.This study forms part of the pre-clinical and clinical collaboration between Karus and the University of Texas MD Anderson Cancer Center, the world鈥檚 leading cancer research and care center. The first part of the trial has been designed to assess the safety of KA2237 alone  dunk panda in relapsed, treatment-resistant B cell lymphoma patients. An expansion cohort study will follow and is scheduled to start in 201  ISLAMABAD:Italian energy giant Eni will start supplying liquefied natural gas (LNG) to Pakistan in December this year, which will be provided to LNG-based power plants being set up in Punjab to tackle prolonged power outages.Pakistan shelves $2b LNG projectAccording to an official, the LNG power plants have been delayed, providing some flexibility to the government in striking a gas supply contract with Eni.He said the Italian company had won adidas campus verdi  a long-term contract after offering some discount in the gas price. Eni came up with the offer in response to two tenders floated by Pakistan ugg mini  LNG Company for gas delivery.One tender was for the short term of five years and the other was for long-term supplies over a period of 15 years. Around 15 companies participated in the short-ter new balance 740 m tender whereas five companies submitted bids for long-term supplies.Two companies Gunvor and Eni were declared successful for quoting the lowest prices.Gunvor quoted 11.62% of crude oil price for short-term LNG deli