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Dr. Grunlan team shape-memory polymer foam serves as a scaffold, spanning gaps in healthy bone and providing a structure for new bone cells to take hold and develop. The polymer is biodegradable, slowly dissolving as bone cells take over and disappearing when the healing process is complete. The polymer already has a long track record of medical use, found in sutures and other biomedical materials. When heated to 140 degrees F, it completely formable, allowing doctors to recreate the shape needed for both structural and cosmetic reconstruction. Wired explains how Grunlan foam works: In lab experi
stanley cup ments, she and her colleagues coated [the foam] with another biodegradable polymer, called polydopamine, that is known to stimulate bone growth. They seeded the polymers with human bone cells, and after a few days saw that the cells were not only multiplying, but producing important bone-forming proteins. Dr. Grunlan says that in humans, the foam could encourage complete bone regrowth in roughly a year. FDA approval is still likely five to 10 years away, but if it happens, it could be a huge boost for reconstructive surgery. [
canada stanley Grunlan Research Lab via Wired] Image: Grunlan Research Lab MedicinePolymersScience
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