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  Our DNA is not indestructible.  nike dunk Th dunk low roughout the course of our lives, DNA can break in response to natural and environmental factors. Thankfully, our bodies have dedicated enzymes and pathways which can glue our broken DNA back together through several different mechanisms, known as DNA repair pathways.Some cancers, however, can hijack these pathways for their own benefit. Susanna Stroik, PhD, andDale Ramsden, PhD, both researchers in theDepartment of Biochemistry and Biophysicsin the UNC School of Medicine and the UNCLineberger Comprehensive Cancer Center, have pieced together the lesser-known DNA repair pathway, called polymerase theta-mediated end joining (TMEJ).The pathway - which has been found to be upregulated in many patients with  nike dunk low hereditary breast cancer, ovarian cancer, and prostate cancer, specifically those involving BRCA1 and BRCA2 mutations - has been laid out step by step ina published articleinNature, and the new knowledge could lead to new therapies for cancer.鈥淧eople wit  PARIS:Defending French Open champion Stan Wawrinka yesterday avoided a repeat of his first-round scare, though he was still made to work hard in a straight-sets win over Japan鈥檚 Taro Daniel.The Swiss third seed won 7-6 (9/7), 6-3, 6-4 on a sunny Court Suzanne Lenglen and is now  adidas campus pink on a six-match winning streak on clay, having warmed u new balance p for Roland Garros by winning the title in Geneva last week.Progress w adidas samba schuhe as by no means straightforward against a skilful opponent ranked 93rd in the world and Wawrinka has yet to switch to his A game.Flawless Nadal races into French Open second roundBut he says it鈥檚 there when he needs it. 鈥淚f you look at the first two matches, for sure I鈥檓 not playing my best tennis, but I know I have my best tennis in me,鈥?the 31-year-old Wawrinka, playing in his 45th consecutive grand slam tournament, told reporters. 鈥淚鈥檓 happy to get through in three sets.鈥漈wice a grand slam champion, Wawrinka needed five sets to scrape past Lukas Rosol in the opening round and found himse