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  Promega and BASF have jointly developed an alternative method to animal studies that can reli yeezy slide ably detect the allergenic potential of substances. Using a new jordan ly developed cell line, the reaction of skin cells to allergenic substances can now be demonstrated in the test tube.Allergic skin reactions involve a variety of biochemical processes. These include the binding of a substance to one of the skin鈥檚 proteins and a resulting stress reaction. Both are early and reliable indicators of a possible allergenic potential of the test substance. In the newly developed cell line, scientists of RWTH Aachen University Hospital have modified a reporter gene from Promega, so that the stress reactions are coupled to a light s nike dunk high ignal. This gene construct was then stably inserted into human skin cell lines. Dr. Katarina Bohm, Marketing Manager of Promega: 鈥淥ur luciferase vectors translate cellular changes into a luminescent signal. This allows stress reactions in skin cells to be easily detected with our   CHITTAGONG:Cyclone Roanu battered the coast of southern Bangladesh on Saturday, forcing half a million people to flee their homes and leaving 20 people dead in floods and rain-triggered landslides.The cyclone damaged hundreds of mud-and-tin houses in two impoverished southern districts, with many low-lying villages inundated by a storm surge that swelled up to seven feet (two metres) high.Authorities took more than 500,000 people into shelters as the cyclone made landfall just after midday local time (0600 GMT), packing winds as strong as 88 kilometres (54 miles) per hour.At least 20 people are known to have died, police said.Fiji residents ordered to stay inside as cyclone looms"Seven people drowned at Banshkhali after the storm surge breached dykes at two places, inundating coastal villages," Shah Alam, a police inspector in Chittagong, told AFP.Three peo adidas campus nere pl nb 1080 e, including a mother and her daughter, drowned on Hatiya island after sea water flooded their village.By e new balance uomo arly evening Saturday