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  Trial initiation followed successful completion of the Clinical Trial Notification (CTN) regulatory process in Australia. The objectives of the study are to characterize the safety profile of ARC-520, determine maximum tolerated dose, and evaluate pharmacokinetics in healthy volunteers. ARC-520 is the first candidate to use Arrowhead鈥檚 proprietary Dynamic Polyconjugate (DPC) delivery platform and includes two distinct siRNA sequences that have pan-genotypic coverage for 99.6% HBV GenBank sequences.The Phase 1 yeezy 700  trial is a single-center, randomized, double-blind, placebo-controlled, single dose-escalation, first-in-human study of ARC-520 administered intravenously to healthy adult volunteers and is being conducted in Melbourne, Australia. Ea adidas yeezy ch dose cohort includes 6 subjects randomized at ratio of 1:2 (placebo:active) to receive a single intravenous injection of either placebo or ARC-520. Arrowhead expects to complete this Phase 1 tr nike dunks high ial in the fourth quarter of 2013 and begin a Phase 2a t  LAHORE:The third national conference of Pakistan Association of Medical Editors (PAME) is starting at the University of Health Sciences (UHS) on Thursday (today). The three-day conference is being organised in collaboration with the Eastern Mediterranea nb zapatillas n Association of Medical Editors (EMAME) and the Health Research Advisory Board. Its theme is Professionalism and Medical Journal Editors. More than 300 ed adidas campus 00's itors, editorial staff, reviewers, referees of biomedical journals, academicians and medical writers will part new balance nere icipate in the event.The programme includes keynote lectures, seminars, panel discussions and five workshops on medical writing, publication ethics, editorship, incorporating technology into medical journalism and peer review for editors, reviewers and authors.A wide range of topics such as research integrity, ethical issues in medical journal editing, role of national regulatory bodies, practical issues in medical editing, authors鈥?and editors鈥?rights and social responsibiliti