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Chronic pain can be an emotionally dr
stanley cup becher aining experience, so antidepressants are sometimes prescribed by doctors to help sufferers with their mental distress. But beyond their typical use, research has also suggested that antidepressants such as serotonin-norepinephrine reuptake inhibitors SNRIs can have an added pain-relief effect. How this exactly happens is still being studied, but its thought the same neurotransmitters that regulate mood and that antidepressants help balance also play
stanley tumbler a part in regulating our sensations of pain, especially pain caused by damaged nerves or a dysfunctional nervous system. At least one antidepressant鈥攖he drug duloxetine, also known as Cymbalta鈥攈as been approved in the U.S. to treat chronic nerve pain and back pain. And organizations such as the American College of Physicians now recommendduloxetine for lower back pain as well. But according to the authors of this new paper, published in the BMJ on Wednesday, the overall effectiveness of antidepressants for treating pain is still uncertain. Their review looked at data from 33 randomized and controlled clinical trials examining the use of antidepressants for chronic back pain as well as osteoarthritis of the hip and knees, including trials that hadnt been included in previous reviews of the evidence, they wrote. These trials involved over 5,300 participants in total. The main outcome they looked at was a reduction in peoples reported score on a pain scale from 1 to 100, w
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was beyond recovery.When Hitomi died, though, researchers also announced that theyd managed to scrape a little bit of data from the satellite and would be detailing it in upcoming papers. Some of that data is out today in a new paper in Nature
stanley cup , which shows Hitomis final observation. It has some fascinating implications for what we know about the role of black holes in galaxy formation.Hitomis final observations were of the Perseus Cluster, a galaxy cluster 240 million light years away with a supermassive black hole at its center. The satellite was able to get this view of the galaxy, as well as to measure its x-ray activity:Researchers expected to see teeming activity in the center of the cluster, but Hitomis final x-ray observations showed very little action. The intracluster gas is quieter than expected, co-author Andrew Fabian of Cambridge University told Gizmodo. We expected that the level would be higher based on the activity of the central galaxy. But the finding isnt just a surprising oasis of calm in a turbulent galaxy. It
stanley termos also gives us insight into just what role black holes play
botella stanley in how galaxies do鈥攐r dont鈥攆orm. Black holes very effectively control the growth rate of galaxies. The surprise is that it turns out that the energy being pumped out of the black hole is being very efficiently absorbed, co-author Brian McNamara of the University of Waterloo told Gizmodo. This hot gas that were looking at with Hitomi is the stuff of the future, its the gas out of which g