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Leqembi is one of sev
stanley thermos mug eral antibody-based drugs that target amyloid beta, a protein that plays an important role in Alzheimers. In those with the disease, a misfolded form of amyloid builds up in the brain over time, causing the development of hardy clumps called plaques. These plaques, along with the accumulation of another misfolded protein called tau, are thought to help gradually destroy the brain. By breaking down or preventing the formation of plaques, its hoped that these drugs
stanley cup can stop or slow peoples cognitive decline. In January 2023, the FDA issued an accelerated approval of Leqembi. This type of approval allows companies to only present indirect evidence that their drug will be clinically meaningful to patients鈥攊n this instance, the reduction of amyloid plaque. But companies are still required to collect data and eventually confirm a drugs clinical benefits in order to receive traditional approval. And it appears that Leqembi has now met that benchmark. Todays action is the first verification that a drug targeting the underlying disease process of Alzheimers disease has shown clinical benefit in this devastating disease, said Teresa Buracchio, acting director of the Office of Neuroscience in the FDAs Center for Drug Evaluation and Research, in a statement released Thursday. In the
stanley mugs pivotal 18-month-long clinical trial that secured Leqembis approval, the drug was found to slow the progression of cognitive decline by 27% in patients compared to those on placebo. Okhg A Tense Traveler Awaits a Crucial Meeting in This First Look at West Africa-Inspired Fantasy Son of the Storm
are all canon and set within the same continuity of the original Blade Runner and its sequel, Blade Runner 2049. Thats what makes this exclusive look at the first cover to Blade Runner 2019 so interesting. Written by Blade Runner 2049 Michael Green and Mike Johnson with illustrations from Andres Guinaldo, Blade Runner 2019 will follow a Blade Runner named Ash through the city of Los Angeles where the original movie was set. The first issues cover, illustrated by Stanley Artgerm Lau, dep
stanley cup icts Ash wielding her gun as she faces off what looks to be Rachael, the experimental Nexus-7 replicant who goes on to play a signif
stanley thermos icant role in the franchises future. Given that Ash and Rachael are going to cross paths somewhere in Los Angeles, its likely that Blade Runner 2019 wont be a one-off story whose plot has no bearing on the larger mythos of the Blade Runner franchise. Just how Ashs story is going to take form is anyones guess until Blade Runner 2019 hits stores sometime this year. For more, make sure youre following us on our new
stanley cup Instagram @io9dotcom.聽 Blade RunnerBlade Runner 2049IndiesMichael Green Daily Newsletter
