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Cmcf We re sedating women with self-care : how we became obsessed with wellness
 If you are looking forward to your first stiff drink afte stanley cup r a dry January, be warned: it may feel bittersweet. You may feel you deserve an alcoholic beverag stanley cup e after toughing it out all month 鈥?but have you forgotten what it feels like to wake up haunted by worries about what you said or did the night before  These post-drinking feelings of guilt and stress have come to be known colloquially as  hangxiety . But what causes them David Nutt, professor of neuropsychopharmacology at Imperial College, London, is the scientist who was fired in 2009 as the governments chief drug adviser for saying alcohol is more dangerous than ecstasy and LSD. I tell him I have always assumed my morning-after mood was a result of my brain having s stanley botella hrivelled like a raisin through alcohol-induced dehydration. When Nutt explains the mechanics of how alcohol causes crippling anxiety, he paints an even more offputting picture.Alcohol, he says, targets the Gaba  gamma-aminobutyric acid  receptor, which sends chemical messages through the brain and central nervous system to inhibit the activity of nerve cells. Put simply, it calms the brain, reducing excitement by making fewer neurons fire.  Alcohol stimulates Gaba, which is why you get relaxed and cheerful when you drink,  explains Nutt.The first two drinks lull you into a blissful Gaba-induced state of chill. When you get to the third or fourth drink, another brain-slackening effect kicks in: you start blocking glutamate, the main excitatory transmitter in  Wtsi Replacing isolation with unreliable Covid tests will put pupils in England at risk
 It s hard to thin stanley cup uk k of a more suprising story than that of Gamu Nhengu. Hers is fairy tale with a modern-day twist; a family fleeing tyranny in Zimbabwe, and a girl who seemed a hair s breadth from X Factor-style fame and fortune, only to have her dreams cruelly curtailed by the heartless bureaucrats at the Home Office.Rumour has it that Gamu was not selected for the X Factor finals because of problems with her immigration status. Whether or not this is true, the family s less modest dream, not of remaining on prime time TV but simply at home in Scotland s Clackmannashire, is now in jeopardy. The Home Office says that the visa extension ap stanley termos plication for Gamu s mother Nokuthula Ngazana was lodged out of time and so has been refused.Then there is the other story of the nation s famously anti  illegal immigrant  tabloids rallying behind a family of, to use their own terminology, i stanley de llegal immigrants. Maybe it takes Cheryl Cole and an ultra glossy talent contest to make Sun readers interested in the systematic unfairness of the UK s immigration and asylum system. Whatever the motive, at least some popular awareness of the fact that there is something wrong with Home Office decision making represents progress.Most immigrants facing deportation have never met Simon Cowell, and do not have 250,000 people campaigning for their right to leave to remain on Facebook campaign. But the fact is, Gamu s story is not as unusual or unrepresentative as it may seem.For example last year a