Hydroxocobalamin seems reasonable for refractory vasoplegia (NO/H₂S scavenging), but I’d frame it as an adjunct after standard measures, not a first move. Also, turgor (hydration sign) and cycloplegia (ophthalmic exam/therapy) address different contexts helpful reminders not to overlink them.
Practical note: during a multi-venue grand rounds, we used simple point-to-point transport to keep timing tight we coordinated via
https://bnlbostonlimo.com/ the smoother flow actually improved the clinical discussion.
OP, in your cases, what criteria define a “responder” to hydroxocobalamin within the first few hours?